Colorectal cancer inter-institutional i2b2 hive

Our work with the i2b2 hive started with a collaboration with the Informatics for Integrating Biology and the Bedside (i2b2) NIH-funded National Center for Biomedical Computing based at Partners Healthcare (Boston, MA) to evaluate the generalizability of the i2b2 “hive.” The latter combines data from a variety of clinical and research data sources with a user-friendly data querying, analysis, and visualization tool improving researchers’ access to clinical data.
We evaluated the i2b2 hive installed in our institution, with an asthma exacerbation prediction use case, and with a broader colorectal cancer health services research use case. The latter combined cancer surveillance and clinical data from different Utah resources including the Utah Cancer Registry, the University of Utah Health Sciences Center, and Intermountain Healthcare.

Publications:

• Meystre, S. M., Stroup, A., & Hartz, A. (2010). A Statewide Colorectal Cancer Database in Utah asClinical Research Use Case for the i2b2 Hive. AMIA Summits Transl Sci Proc, CRI.
• Deshmukh, V. G., Meystre, S. M., & Mitchell, J. A. (2009). Evaluating the informatics for integrating biology and the bedside system for clinical research. BMC Medical Research Methodology, 9, 70. 
• Meystre, S. M., Deshmukh, V., & Mitchell, J. A. (2009). A Clinical Use Case to Evaluate the i2b2 Hive: Predicting Asthma Exacerbations. AMIA Annu Symp Proc, 2009, 442–446.